Category Archives: Vitamin D Studies

Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency

Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency

Vitamin D deficiency is a common risk factor for multifactorial diseases, and it seems to be associated with growth hormone deficiency (GHD). Vitamin D could prevent dental caries. The goal of this study was to identify whether there is an association between hormonal therapy with growth hormone (GH), vitamin D3 supplementation, vitamin D3 levels, and the occurrence of caries among children affected by GHD.

Vitamin D Deficiency and Oral Health: A Comprehensive Review

Vitamin D Deficiency and Oral Health A Comprehensive Review

Vitamin D (VD) levels have been gaining growing attention in Oral Health. During growth and adulthood, VD deficiency (VDD) is associated with a wide variety of oral health disorders, and impaired VD synthesis may expedite some of these conditions. In children, severe VDD can induce defective tooth mineralization, resulting in dentin and enamel defects. As a consequence, these defects may increase the risk of the onset and progression of dental caries. Further, VDD has been associated with higher prevalence of periodontitis and gingival inflammation, and several recent preclinical and clinical studies have unveiled potential pathways through which Vitamin D may interact with the periodontium. VDD correction through supplementation may contribute to a successful treatment of periodontitis; however, alveolar bone regeneration procedures performed in baseline VDD patients seem more prone to failure. Vitamin D may also be linked with some oral pathology entities such as certain oral cancers and events of osteonecrosis of the jaw. This review aims to provide comprehensive evidence of how VD levels should be considered to promote good oral health, and to summarize how VDD may hamper oral development and its role in certain oral conditions.

Vitamin D deficiency in Early Implant Failure: Two Case Reports

An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants from different manufacturers in the molar region of the mandible. In the case of bone grafting in the first patient, all implants were placed in a two-stage procedure. All implants had to be removed within 15 days after implant placement. Vitamin D serum levels were measured: Both patients showed a vitamin D deficiency (serum vitamin D level <20 μg/l). After vitamin D supplementation, implant placement was successful in both patients. Prospective, randomized clinical trials must follow to affirm the relationship between vitamin D deficiency, osteoimmunology, and early implant failure.

The Biological Activities of Vitamin D and Its Receptor in Relation to Calcium and Bone Homeostasis, Cancer, Immune and Cardiovascular Systems, Skin Biology, and Oral Health

Vitamin D plays an important role in calcium homeostasis and bone metabolism, with the capacity to modulate innate and adaptive immune function, cardiovascular function, and proliferation and differentiation of both normal and malignant keratinocytes.

Vitamin D Deficiency and its Effects on Tooth Structure and pulpal changes

Effects on Tooth Structure and pulpal changes

Vitamin D is a steroid hormone that produced primarily by sunlight exposure or obtained from dietary sources, including supplements. The persons who are normally at risk of Vitamin D deficiency are those with scarce of sun exposure and diminished intestinal absorption or limited oral intake. Teeth are nothing but mineralized structure which is enclosed by alveolar bone and are developed by 3 different hard tissues such as dentin, enamel, and cementum. Vitamin D plays a predominant vital part in the tooth and bone mineralization, and it can result in rachitic tooth when the levels get unregulated. Studies suggest that Vitamin D deficiency causes hypocalcified dentin and delayed tooth eruption; thus, representing that Vitamin D has a crucial role in dentin formation as well. The beneficial effects of vitamin D on oral health are not only limited to the direct effects on the tooth mineralization but are also applied through ability to stimulate the production of anti-microbial peptides. In this article, we will briefly discuss the influence on Vitamin D level on the oral and pulpal health.

Importance of vitamin D in dentistry: Could it play a role in resistance to infectious diseases?

Importance of vitamin D in dentistry

Vitamin D is a steroid hormone that is obtained through diet or synthesised in the skin from cholesterol when the skin receives adequate sun exposure (the main means of obtaining the vitamin). Unfortunately, exposure to direct sunlight has declined dramatically in today’s society with the increase in the number of office jobs. Furthermore, as we grow older, our ability to absorb vitamin D decreases. Vitamin D deficiency is a global public health problem, affecting all age groups. Recent studies have shown that about 70% of society is deficient in vitamin D.1

Vitamin D Deficiency and Oral Health: A Comprehensive Review

Vitamin D (VD) levels have been gaining growing attention in Oral Health. During growth and adulthood, VD deficiency (VDD) is associated with a wide variety of oral health disorders, and impaired VD synthesis may expedite some of these conditions. In children, severe VDD can induce defective tooth mineralization, resulting in dentin and enamel defects.